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Give him kisses and let the morning begin in its own natural

These mutations result in a failure to assemble fully functional multimeric protein. Inherited MASP 2 deficiency has been described as the result of a mutation causing the exchange of aspartic acid with a glycine at position 105, a position in the first domain, CUB1, involved in calcium binding. This mutation abolishes the binding to MBL and ficolins, and deprives MASP 2 of functional activity.

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